Proper dos - overdose - Back Pain Causes, Relief and Natural Treatment


NOTE: Infusions beyond 21 hours should be considered when the absorption and/or half-life of acetaminophen (APAP) may be prolonged (., suspected massive overdose, concurrent ingestion of other substances, patients with preexisting liver disease). In these cases, ALT/AST, INR, and APAP concentrations should be measured after the last maintenance dose. If the APAP concentration is still detectable, ALT/AST are still increasing, or the INR remains elevated, the infusion may be continued. If the infusion is extended beyond 21 hours, the treating physician should contact either the US poison center (1-800-222-1222) or a special health professional assistance line for APAP overdose (1-800-525-6115) for assistance with dosing recommendations.

Accidental ingestion of even one dose of methadone hydrochloride tablets, especially by children, can result in a fatal overdose of methadone [see WARNINGS AND PRECAUTIONS ].


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